Lesson 5
6. Clonidine: Wallace Study Conclusions
Clonidine study conclusions? Clonidine is an alternative
drug to beta blockers in patients who are at risk for perioperative
beta blockade who can not tolerate a beta blocker. BBAC with prophylactic
administration of Clonidine reduced incidence of myocardial ischemia,
30-day (p = 0.03), and 2 year mortality (p = 0.04).
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Clonidine Study Conclusions
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Prophylactic Administration
of Clonidine 0.2 mg po the night prior to surgery, 0.2
mg po the day of surgery, and a TTS-2 patch for 4 days
reduces the incidence of myocardial ischemia by 50% in
patients at risk for coronary artery disease undergoing
non-cardiac surgery |
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Prophylactic Administration
of Clonidine reduced 30-day (p = 0.03) and 2 year mortality
(p = 0.04). |
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